Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5727235 | Journal of Vascular and Interventional Radiology | 2016 | 10 Pages |
Abstract
The coagulopathy of liver disease is distinctly different from therapeutic anticoagulation in a patient. Despite stable elevated standard clot-based coagulation assays, nearly all patients with stable chronic liver disease (CLD) have normal or increased clotting. Common unfamiliarity with the limitations of these assays in CLD may lead to inappropriate and sometimes harmful interventions, including blood product transfusions before a procedure. Knowledge of the distinct hemostatic alterations in CLD can allow identification of the small subset of patients with clinically significant coagulopathy who can benefit from hematologic optimization before invasive procedures.
Keywords
ACLFAASLDHVPGDDAVPrFVIIaALFFFPINRCLDvWFAPTTDICDIC, Disseminated intravascular coagulationChronic liver diseaseDesmopressin acetateactivated partial thromboplastin timeHepatic venous pressure gradientTissue factorVon Willebrand factorrecombinant Factor VIIaacute-on-chronic liver failureAcute liver failureInternational Normalized Ratiofresh frozen plasma
Related Topics
Health Sciences
Medicine and Dentistry
Radiology and Imaging
Authors
Gia A. MD, Rachita MD, Ziv J MD, Hillary S. MD, Patrick G. MD, Neeral L. MD, Stephen H. MD,