New horizons in transplantationLiver transplantationCorrelation Between Survival Interval and CD4+ T-Cell Intracellular ATP Levels in Liver Transplant Recipients

•We analyzed the potential correlation between post-liver transplantation survival interval and CD4+ T-cell iATP levels, and described the distribution of CD4+ T-cell iATP levels in liver transplant recipients.•The peak CD4+ T-cell iATP levels typically occurred within the first 3 postoperative months.•Post-liver transplantation survival interval is correlated with CD4+ T-cell iATP levels.

ObjectiveThe objectives of this study were to analyze the potential correlation between post-liver transplantation survival interval and CD4+ T-cell intracellular ATP (iATP) levels, and to describe the distribution of CD4+ T-cell iATP levels in liver transplant recipients.MethodsThis was a retrospective analysis of clinical data of 273 patients who underwent liver transplantation from July 2010 to October 2012 in our center and achieved long-term stable survival. CD4+ T-cell iATP level was detected using Cylex ImmuKnow assay. Post-liver transplantation survival was analyzed.ResultsCD4+ T-cell iATP level significantly differed among patients with different post-liver transplantation survival intervals. The peak CD4+ T-cell iATP levels typically occurred within the first 3 postoperative months.ConclusionsPost-liver transplantation survival interval is correlated with CD4+ T-cell iATP levels.