Original: Works: Case reportsPancreasSinistral Portal Hypertension After Live Segmental Pancreas Donation: A Long-Term Sequelae Presenting With Life-Threatening Upper Gastrointestinal Hemorrhage

•The first successful live segmental pancreas donation (LSPD) was performed in 1979.•Sinistral portal hypertension (SPH) is a rare cause of gastrointestinal hemorrhage.•Variceal hemorrhage from SPH has never been reported as a complication of LSPD.•We present the case of a donor who developed SPH years after LSPD.

IntroductionVariceal hemorrhage from sinistral portal hypertension has never been reported as a complication of live pancreas donation.Case ReportWe present a 68-year-old patient who underwent a simultaneous live-donor laparoscopic segmental pancreatectomy and nephrectomy for the purposes of donating to her daughter. Her postoperative course was significant for an episode of acute pancreatitis with a pseudocyst formation. More than a decade later, she presented with variceal hemorrhage from sinistral portal hypertension, which after a diagnostic work-up, prompted a laparoscopic splenectomy.DiscussionSinistral portal hypertension is a long-term complication of live-donor pancreas donation.