| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5729703 | European Urology Focus | 2016 | 7 Pages |
Abstract
We found that variants of CYP3A4, a gene involved in drug metabolism, are associated with sunitinib toxicity. This information may help in better selection of patients for targeted therapies in metastatic renal cell carcinoma.
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Authors
Guillermo de Velasco, Kathryn P. Gray, Lana Hamieh, Yuksel Urun, Hallie A. Carol, Andre P. Fay, Sabina Signoretti, David J. Kwiatkowski, David F. McDermott, Matthew Freedman, Mark M. Pomerantz, Toni K. Choueiri,