| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5730350 | The Journal of Sexual Medicine | 2016 | 14 Pages |
Abstract
Collectively, these data demonstrate that testosterone improves the relaxation of vascular smooth muscle cells through the NO-cGMP pathway, and that testosterone and 17β-estradiol are necessary to maintain a functional contractile and relaxant machinery in the clitoris. This new concept might provide support for the concomitant use of estrogen and testosterone during the treatment of sexual arousal disorders related to hormonal imbalance or insufficiency.
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Authors
Paolo PhD, Ilaria PhD, Sandra PhD, Chiara BSc, Francesca BSc, Annamaria PhD, Elena PhD, Elisa MD, Edoardo MD, Massimiliano MD, Mario MD, Linda MD, PhD,