| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5730376 | The Journal of Sexual Medicine | 2017 | 9 Pages |
Abstract
Our results suggest that sGC is the sole target of NO in erectile physiology. Furthermore, this study provides indirect evidence that, in addition to sGCα1β1, sGCα2β1 is important for erectile function. In addition, the significant relaxation observed in sGCβ1ki/ki mice with the cumulative addition of the sGC activator BAY 58-2667 indicates that sGC activators might offer value in treating erectile dysfunction.
Related Topics
Health Sciences
Medicine and Dentistry
Urology
Authors
Kelly PhD, Bart PhD, Charlotte MSc, Robrecht PhD, Emmanuel S. PhD, Peter PhD, Johan PhD,