Case reportSclerosing angiomatoid nodular transformation of the spleen presenting rapid growth after adrenalectomy: Report of a case

•SANT displayed a rapid growth in size from 20 mm to 70 mm during 3 years after adrenalectomy.•Splenectomy was performed by hand assisted laparoscopic surgery (HALS).•Corticosteroids might be useful for treating SANT.

IntroductionSclerosing angiomatoid nodular transformation (SANT) is a rare benign lesion with an unknown natural history and pathogenesis. So far fewer than 100 cases were documented, but detailed incidence and prevalence are unknown.Presentation of caseWe report a case of SANT of the spleen in a 37-year-old man that showed rapid growth after adrenalectomy for primary aldosteronism. Computed tomography showed a nodule in the spleen that increased in size from 2.0 cm to 7.0 cm during 3 years of observation.DiscussionThis case is reported because data regarding growth rates and natural history of these lesions are limited and few cases have been reported to show the rapid growth progression seen in this case.ConclusionDecreases in glucocorticoid concentrations following adrenalectomy may have contributed to the rapid growth of SANT of the spleen, because SANT is considered to be related to immunoglobulin G4-associated disease.