Case ReportCongenital embryonal rhabdomyosarcoma; multiple lesions

•We report a neonate patient with congenital rhabdomyosarcoma that had multiple lesions.•This rare condition should be considered in the differential diagnosis of neurofibroma and lymphoma in neonates.•The rapid diagnosis of congenital rhabdomyosarcoma can prevent disease progression by appropriate chemotherapy regimen.•It was very interesting that lesions were multiple and affected different parts of the body.•Although bone marrow involvement by embryonal rhabdomyosarcoma is very rare, it should be considered even in early manifestation in a neonate.

IntroductionCongenital or neonatal rhabdomyosarcoma (RMS) is a rare soft tissue tumor with the most common sites of origin in genitourinary tract, head, and neck regions and extremities are less commonly involved.Presentation of caseIn this paper, a case of embryonal RMS with skin lesions, lymph nodes metastasis, and bone marrow metastasis is reported for a 1-month old female patient.DiscussionThis study presents how within 8-months of chemotherapy, the lesions got subsided and the patient became disease free.ConclusionMultiple congenital rhabdomyosarcoma of neonate is a rare finding that should be considered as differential diagnosis of lymphoma and neurofibroma.