Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5733709 | Journal of Surgical Research | 2017 | 7 Pages |
Abstract
Taken together, these data suggest that the vascular response to stretch injury is associated with release of ATP and activation of the P2X7R/P38 MAPK pathway, resulting in contractile dysfunction. Modulation of this pathway in vein grafts after harvest and before implantation may reduce the vascular response to injury.
Keywords
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Authors
Christy M. MD, Weifung PhD, Olukemi MS, Kalyan S. Chadalavada, Padmini PhD, Joyce PhD, Colleen M. MD,