| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5733870 | Journal of Surgical Research | 2017 | 6 Pages |
Abstract
Enhancing 5-HT signaling in mice increases VH, CD, EH, and crypt cell proliferation in the intestinal mucosa. 5-HT-associated growth did not alter the cellular composition of the villi. Serotonin may represent an important physiologic regulator of intestinal growth and adaptation and holds promise as a target for therapies aimed at enhancing intestinal recovery after injury or mucosal surface area loss.
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Authors
John J. MD, MHS, Neeru PhD, Michaela C. MD, MHS, Eleanor D. MD, Robert A. MD,