| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5733895 | Journal of Surgical Research | 2017 | 9 Pages |
Abstract
Our study represents the initial evidence showing that TNF plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF signaling by ablation of TNFR1 and TNFR2 genes increased SDF-1 expression in the heart. These data expand on TNF signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR-derived actions in hopes of advancing ischemic heart injury treatments.
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
Meijing MD, Lina MS, Chunyan MD, I-Wen MD, PhD, Mark W. MD,