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Inhibition of acquired-resistance hepatocellular carcinoma cell growth by combining sorafenib with phosphoinositide 3-kinase and rat sarcoma inhibitor

Article ID Journal Published Year Pages File Type
5733939 Journal of Surgical Research 2016 9 Pages PDF
Abstract
Our studies have showed that both inhibitors of PI3K/mTOR and RAS/ERK signaling are potentially effective antihepatocellular carcinoma drugs especially in treating sorafenib-resistant hepatocellular carcinoma.
Keywords
PI3KERKMDR1SorafenibDrug resistanceHepatocellular carcinoma
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Health Sciences Medicine and Dentistry Surgery
Preview
Inhibition of acquired-resistance hepatocellular carcinoma cell growth by combining sorafenib with phosphoinositide 3-kinase and rat sarcoma inhibitor
Authors
Chang-Hao MMed, Xiang MMed, Hong-Wei MD,
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