| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5734013 | Journal of Surgical Research | 2017 | 8 Pages |
Abstract
SRT1720 treatment attenuates multiorgan injury in septic mice. SRT1720 treatment also decreases the production of proinflammatory cytokines and reduces inflammasome activation. Thus, pharmacologic stimulation of Sirt1 may present a promising therapeutic strategy for sepsis.
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Authors
Adam MD, PhD, Weng-Lang PhD, Laura W. MD, Salil R. MD, Jose M. MD, Jeffrey M. MD, Gene F. MD, Ping MD,