Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734090 | Journal of Surgical Research | 2017 | 39 Pages |
Abstract
Piperidone analogs of curcumin exhibited enhanced antitumor effects in vitro as opposed to their parent compound. Even more, this enhanced cell death profile may be partially attributed to the ability of these compounds to activate the AHR. Further study of synthetic curcumin analogs as chemopreventives and chemoadjuncts in CRC is warranted. Also, more generally, the AHR may represent a potential putative target for novel anticancer agents for CRC.
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
Bryant W. BS, Patrick R. BS, Mitchell G. Depke, Manabu PhD, James BS, Lesley PhD, Rhonda J. PhD, Gregory D. MD, PhD,