Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734225 | Journal of Surgical Research | 2017 | 11 Pages |
Abstract
By targeting SOCS3 and then enhancing proliferating IL-6/STAT3 signaling pathway, hepatic overexpression of miR-203 can facilitate the initiation of liver regeneration and enhance the potency of liver regeneration after 70% PH in cirrhotic rat. Together with the tumor suppressive effect on HCC, miR-203 would be an ideal candidate for promoting liver regeneration in HCC patients undergoing liver resection without the risk of tumorigenesis or cancer recurrence.
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Authors
Xiao-Bo PhD, Xiao-Bo MS, Zhen-Xing MD, Xian-Jian MS, Ming-Qing MD, PhD,