Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734239 | Journal of Surgical Research | 2017 | 12 Pages |
Abstract
Changes to the microvasculature during systemic inflammation are most pronounced in small intestine. Melatonin selectively diminishes these changes to small intestinal microvasculature, probably by reducing the local immune cells recruitment. However, changes to the small intestine are not decisive for the survival. We assume that the therapeutic benefit of melatonin is more likely in local intestinal inflammation.
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Authors
Maren Oude PhD, Vivien Candmed, Herbert MD, PhD, Katharina PhD,