Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734404 | Surgery | 2017 | 7 Pages |
Abstract
Our data suggest that the checkpoint protein, PD-1, plays an important role in controlling the immune response to sepsis in the neonate, ultimately affecting sepsis-related mortality in this neonatal murine model of sepsis. Akin to adult studies, these data further emphasize the potential therapeutic target for PD-1 across a spectrum of septic patients.
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Authors
Whitney A. MD, Eleanor A. MD, Daithi S. MD, Philip A. MD, William G. MD, Alfred PhD,