Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734405 | Surgery | 2017 | 11 Pages |
Abstract
Calpain activation in metabolic syndrome is a potential contributor to cardiac dysfunction in metabolic disorders with ischemic background. We suggest that calpain inhibition downregulates NFkB signaling in the vessel walls, which might be useful for improving myocardial blood flow in ischemic conditions.
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Authors
Brittany A. MD, Ashraf A. MD, Nassrene Y. MD, PhD, Sharif A. MA, Benedikt J.V. BS, Richard T. PhD, Anny PhD, Frank W. MD,