Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5734777 | Surgery | 2017 | 9 Pages |
Abstract
Our study provides evidence that PGE2 can inhibit directly pancreatic ductal adenocarcinoma cell growth through an EP4-mediated mechanism. Together with our gene expression and survival analysis, this observation suggests a protective role of EP4 receptors in human pancreatic ductal adenocarcinoma that expresses E-type prostaglandin receptors.
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Authors
Andrea MD, James BSc, Steven PhD, Hui-Hua PhD, O. Joe MD, David W. MD, Enrique PhD, Guido MD,