Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5735298 | Behavioural Brain Research | 2017 | 9 Pages |
Abstract
PDE7 inhibitor induced anxiolytic and anorexigenic like behavior depending on the dose used. Results supported hypothalamic TRH mediated feeding-reduction effects, and accumbal TRH mediation of inhibitor-induced anxiolysis. Thus, an i.p dose of this inhibitor might be reducing anxiety with no change in feeding, which could be useful for obese patients.
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Authors
M.I. Valdés-Moreno, V. Alcántara-Alonso, E. Estrada-Camarena, G. Mengod, M.I. Amaya, G. Matamoros-Trejo, P. de Gortari,