| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5735911 | Current Opinion in Behavioral Sciences | 2017 | 7 Pages |
Abstract
Individual differences in temperament are associated with psychopathology in humans. Moreover, the relationship between temperament and anxiety-, depression-, PTSD- and addiction-related behaviors can be modeled in animals. This review will highlight these relationships with a focus on individual differences in the response to stressors, fear conditioning and drugs of abuse using animals that differ in their response to a novel environment. We will discuss behavioral and neurobiological commonalities amongst these behaviors with a focus on the hippocampus and, in particular, growth factors as promising novel targets for therapeutic intervention.
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Authors
Cortney A Turner, Shelly B Flagel, Peter Jr, Stanley J Jr, Huda Akil,