| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5736411 | Brain Research Bulletin | 2017 | 9 Pages |
Abstract
Results displayed that supplementation with zeaxanthin reduce blood glucose, improve cognitive deficit, survive neural cell, increase p-AKT level, inhibit Cleaved caspase-3 level and NF-κB nuclear transcription in hippocampus. This study demonstrated that zeaxanthin ameliorate diabetes-related cognitive deficit may by means of protecting neural cell from hyperglycemia involved in AKT/NF-κB signaling pathway. This study may provide a potential therapeutic approach for the prevention of diabetes- associated cognitive deficit.
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Authors
Xiaoyan Zhou, Shanshan Wang, Xin Ding, Li Qin, Yizhen Mao, Lei Chen, Wei Li, Changjiang Ying,