| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5736425 | IBRO Reports | 2017 | 33 Pages |
Abstract
We used multiple electrode arrays to characterize and compare the anticonvulsant mechanisms of Mannitol and Phenytoin. Phenytoin decreased the voltage, duration and spatial spread of rhythmic repetitive, ictal-like activity. In contrast, Mannitol did not significantly affect voltage, duration and spatial spread of rhythmic repetitive, ictal-like activity but rather it inhibited the rate of epileptiform discharges.
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Authors
Ruggero Serafini,