Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5737023 | Current Opinion in Neurobiology | 2017 | 7 Pages |
Abstract
Although earlier models of brain circuitry controlling wake-sleep focused on monaminergic and cholinergic arousal systems, recent evidence indicates that these play mainly a modulatory role, and that the backbone of the wake-sleep regulatory system depends upon fast neurotransmitters, such as glutmate and GABA. We review here recent advances in understanding the role these systems play in controlling sleep and wakefulness.
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Authors
Clifford B Saper, Patrick M Fuller,