Organization of spatial frequency in cat striate cortex

•Large-scale organization of spatial frequency maps in cat area 17 was studied.•SF organization in cat A17 displayed a global asymmetrical unimodal distribution.•The cortices representing horizontal meridian preferred the highest SF.

Primary visual cortex, the first cortical stage of visual information processing, is represented by diverse functional maps that demonstrate the selectivity for specific visual features such as spatial frequency (SF). Although the local organization of SF maps in cat area 17 (A17) has been largely investigated, the global arrangement remains elusive. To address this unclear aspect, we evaluated the organization of SF maps within A17 by intrinsic signal optical imaging and extracellular electrophysiological recording. Our results explicitly showed that SF organization in cat A17 displayed a global asymmetrical unimodal distribution. In particular, we found the highest SF preference within the global distribution concentrated around the horizontal meridian. These results significantly contribute to a more comprehensive understanding of the SF organization in visual cortex.