Article ID Journal Published Year Pages File Type
5738037 Neuroscience Letters 2018 17 Pages PDF
Abstract
Oxidative DNA damage plays an important role in the early stages of PD, whereas during the progression of the disease the process is more complex, and other mechanisms are in the foreground. The measurement of 8-OHdG might be used as an “early-stage marker”, whereas the decrease of 8-OHG in CSF might reflect the degree of neurodegeneration during the disease progression, suggesting its utility as a prognostic marker of advanced PD stages.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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