Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5738697 | Neuroscience Letters | 2017 | 6 Pages |
Abstract
These data suggest that CAW, and several of the compounds found therein, can improve dendritic arborization and synaptic differentiation in the context of Aβ exposure which may underlie the cognitive improvement observed in response to the extract in vivo. Additionally, since CAW, and its constituent compounds, also improved these endpoints in WT neurons, these results may point to a broader therapeutic utility of the extract beyond Alzheimer's disease.
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Authors
Nora E. Gray, Jonathan A. Zweig, Charles Murchison, Maya Caruso, Donald G. Matthews, Colleen Kawamoto, Christopher J. Harris, Joseph F. Quinn, Amala Soumyanath,