Enhancing and improving the extraction of omega-3 from fish oil

•Blue fish oil is rich in omega-3 fatty acids, in particular of DHA and EPA.•Omega-3 extracts are valued nutritional support to the bottom of the nutritional pyramid.•We review claims concerning health benefits to children and adults.•Progress towards the greener production of better omega-3 extracts is possible.

Omega-3 fatty acids DHA and EPA derived from fish oil are widely marketed across the world as valued dietary supplements offering numerous health benefits to children and adults alike. Traditional extraction processes are energy intensive and use organic solvents. Green and sustainable alternatives are needed with the aim to significantly expand and improve the production of omega-3 extracts, especially with the aim to obtain these essential polyunsaturated fatty acids from fish processing waste available in >20 million tonnes/year amount.