Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5775474 | Applied Mathematics and Computation | 2017 | 6 Pages |
Abstract
In recent years, the constructive role of internal noise in mesoscopic system has attracted much attention. Because the external noise is also unavoidable, it is more practical to study the influence of internal noise with the existence of external noise in these systems. By constructing a mesoscopic stochastic model of a cell system, we discussed the influence of internal noise on the detection of hormonal signal with the existence of external noise. Results have found that internal noise can play a constructive role when external noise intensity is at some regions (Dâ¯<â1.0 and Dâ¯>â1.16), so that the cell system can effectively detect the weak hormonal signal through intracellular calcium spikes. This phenomenon is different from the results found previously, where it was found that internal noise always played a destructive role except for at very small external noise intensity.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Hongying Li, Chengli Yao,