| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 578027 | Journal of Hazardous Materials | 2012 | 8 Pages |
Abstract
⺠ZnO particles had similar toxicity in MH-S cells and Ana-1 cells. ⺠Zinc ions induced metallothionein synthesis to reduce oxidative damage at low dose. ⺠At high dose, excessive zinc destroyed mitochondrial function, caused cell necrosis. ⺠Zinc ions first cause toxicity in MH-S cells, and their toxicity exist a threshold. ⺠Toxic difference of ZnO particles depended on the role of nondissolved ZnO particles.
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Authors
Jinyang Zhang, Wenhua Song, Jing Guo, Jinhua Zhang, Zengtian Sun, Feng Ding, Minling Gao,