Determination of perfluorooctane sulfonate and perfluorooctanoic acid in food packaging using liquid chromatography coupled with tandem mass spectrometry

► PLE and LC-MS/MS was employed to determine PFOS and PFOA in food packaging. ► Highest concentration of PFOS was found in fast-food container samples (92.48 ng dm−2). ► Highest concentration of PFOA was found in ice cream cup samples (16.91 ng dm−2). ► Saliva simulant could leach PFOS and PFOA from the thickest paper samples group (≤1 dm2 g−1) at 7.01 and 6.41 ng dm−2. ► Greater thickness and less area might release larger quantities of coated/added PFOS or PFOA.