| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5788879 | Science Bulletin | 2017 | 6 Pages |
Abstract
Gold-catalyzed nucleophilic addition to terminal alkynes has received considerable interest in the past decade, as this chemistry offers a highly efficient and regioselective way for CC, CH and CX bond formation. However, such a nucleophilic addition mainly involves a Markovnikov addition. In this short review, the recent progress of the gold-catalyzed 5-endo-dig cycloisomerization-initiated tandem reactions by utilizing the steric strain in ring formation to achieve an anti-Markovnikov regioselectivity was reviewed, including the scope of reactions, mechanism and synthetic applications.
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Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Chao Shu, Long Li, Tong-De Tan, Ding-Qiang Yuan, Long-Wu Ye,