| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5806661 | Current Opinion in Virology | 2016 | 8 Pages |
Abstract
â¢Heterologous infections can impact the outcome of HCV infection.â¢HCV infection can influence the outcome of heterologous virus infections.â¢Mechanisms are polarization of TH1/TH2, induction of cytokines and T cell cross-reactivity.
Heterologous immunity can impact the natural course of subsequent infections by different mechanisms such as polarization of TH1/TH2 responses, induction of cytokines and T cell cross-reactivity. In the case of hepatitis C virus (HCV) infection, heterologous immunity helps to explain the high variability in clinical outcomes. This review discusses how other infections can alter the natural course of hepatitis C and how HCV infection influence unrelated infections.
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Authors
Markus Cornberg, Heiner Wedemeyer,