| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5806932 | Current Opinion in Virology | 2012 | 8 Pages |
Abstract
⺠Experimental methods to study virus-host interactomes including mammalian validation systems. ⺠Yeast-two-hybrid (Y2H) as classical high-throughput method for protein-protein interaction analysis. ⺠Cellular antiviral drug target candidates. ⺠HTY2H screening identifies immunophilins (cyclophilins and FK506-binding proteins) as anticoronaviral targets. ⺠cyclosporine A has broad-spectrum anticoronaviral potential.
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Authors
Yue Ma-Lauer, Jian Lei, Rolf Hilgenfeld, Albrecht von Brunn,