| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5806963 | Current Opinion in Virology | 2012 | 7 Pages |
Abstract
⺠Rhinovirus is a ubiquitous virus and the usual cause of the common cold, yet little is known regarding its pathogenic mechanisms. ⺠The upper and lower airways are the primary targets of RV, but, surprisingly, this virus causes little cytopathology. ⺠Many patients will have positive tests to RV, yet remain subclinical. ⺠The host epithelial barriers and both innate and adaptive immune responses influence the reaction of the host. ⺠The various immune responses lead to the distinct outcomes from subclinical to severe and even life-threatening infections.
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Authors
Joshua L Kennedy, Ronald B Turner, Thomas Braciale, Peter W Heymann, Larry Borish,