| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5806979 | Current Opinion in Virology | 2012 | 9 Pages |
The characterization of viral genomes has accelerated due to improvement in DNA sequencing technology. Sources of animal samples and molecular methods for the identification of novel viral pathogens and steps to determine their pathogenicity are listed. The difficulties for predicting future cross-species transmissions are highlighted by the wide diversity of known viral zoonoses. Recent surveys of viruses in wild and domesticated animals have characterized numerous viruses including some closely related to those infecting humans. The detection of multiple genetic lineages within viral families infecting a single host species, phylogenetically interspersed with viruses found in other host species, reflects past cross-species transmissions. Numerous opportunities for the generation of novel vaccines will arise from a better understanding of animal viromes.
⺠There are numerous sources of samples for animal virus discovery. ⺠Many simple molecular methods exist for the characterization of novel viruses. ⺠Some human viruses have genetically close animal counterparts. ⺠Future emerging human viruses may arise from any animal viral families. ⺠Disease association and causation studies are needed for many new animal viruses.
