Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5810584 | Medical Hypotheses | 2015 | 4 Pages |
Abstract
In vivo formed HOBr as a long-lived product with a high biological activity induces the hypoxic tumor cell damage via many unique mechanisms. A local application or inhalation of an N2O-O2 mixture before or during the radiotherapy to enhance the saturation of tissues with N2O is a key prerequisite. Since the extracellular concentration of Brâ ions is very low (0.02-0.05Â mM), an oral or local application of NaBr should be used to shift the extracellular concentration of Brâ ions to the mM region.
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Authors
P. Billik,