Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5812152 | Medical Hypotheses | 2013 | 9 Pages |
Abstract
The predicted binding energy values showed that our designed novel peptide demonstrated strong binding affinity for Hsp90α. Subsequently, the binding affinity of Hsp90α for mutant p53 was shown to be reduced substantially indicating a strong inhibitory potential of the designed peptide PEP73 (INSAYKLKYARG) for Hsp90α.
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Authors
Uday Kumar Gupta, Sailendra Mahanta, Subhankar Paul,