The neurophysics of psychiatric diagnosis: Clinical brain profiling

Each of these organizational brain functions is predicted to involve a relatively specific neuronal circuitry system in the brain. The circuitry of the nigra-striautum-cortex, are a component of the connectivity balance stabilizers and regulators, a type of neural complexity pacemaker. Thus a patient that rates high on phenomenology related to functional psychosis indicating a disturbance to connectivity balance will have disturbances that will show up in appropriate signal processing imaging of the nigra-striautum-cortex circuitry. The circuitry of thalamus-amygdala-cortex and related pathways are relevant for neuronal matching and constraint frustration. In this respect the patients scoring high on mood and anxiety disorders are predicted to suffer from perturbation shown on appropriate imaging involving the thalamus-amygdala-cortex circuitries. The hippocampus is related to the formation of internal configurations thus those patients rating highest on parameters related to personality organization and maturation will show alterations in the hippocampal organization and activation indicating deficient organizations of internal configurations.