| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5813322 | Neuropharmacology | 2016 | 16 Pages |
Abstract
JNJ-40411813 elicited comparable functional responses in rodents and men if circadian time of dosing was taken into account. These findings underscore the translational potential of sleep mechanisms in evaluating mGluR2 therapeutics when administered at the appropriate circadian time.
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Authors
A. Ahnaou, P. de Boer, H. Lavreysen, H. Huysmans, V. Sinha, L. Raeymaekers, T. Van De Casteele, J.M. Cid, L. Van Nueten, G.J. Macdonald, J.A. Kemp, W.H.I.M. Drinkenburg,