Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5813338 | Neuropharmacology | 2016 | 12 Pages |
Abstract
Genetic loss of the 5-HT2A receptor compromised the activity of chronic treatment with SSRIs, making this receptor a putative marker to predict ADs response.
Keywords
DcxSNRIsMDEvHPCSSRIs5-bromo-2-deoxyuridineDRNMPFC5-HTTMDDADS5-HTMAF5-HT1A receptor5-HT2A ReceptorBDNFMajor depressive disorderElectrophysiologyBrdU5-HT transporterAntidepressant drugsdoublecortinSerotoninserotonin transporterAntidepressantminor allele frequencyMajor depressive episodemedial prefrontal cortexserotonin norepinephrine reuptake inhibitorSSRIdorsal raphe nucleusHippocampusventral hippocampusPolymorphismSingle nucleotide polymorphismsSNPGenetic
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Authors
Gaël Qesseveur, Anne Cécile Petit, Hai Thanh Nguyen, Lionel Dahan, Romain Colle, Samuel Rotenberg, Isabelle Seif, Pauline Robert, Denis David, Jean-Philippe Guilloux, Alain M. Gardier, Céline Verstuyft, Laurent Becquemont, Emmanuelle Corruble,