| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5813651 | Neuropharmacology | 2015 | 17 Pages |
Abstract
Purines are critical regulators of neurotransmission in human ENS. Purinergic signaling involves P2X1, P2X2, P2X3 channels, P2X1 + P2X2 co-localization and inhibitory P2Y or A3 receptors. These are potential novel therapeutic targets for neurogastroenterology.
Keywords
IBSEHNAENSIP3FTSARL67156LSCMIBDmRNAFITCCa2+fEPSPsinositol-1,4,5-triphosphate[Ca2+]iadenosine 5′-triphosphateEndogenous adenosineATPSubmucous plexusinflammatory bowel diseasesmessenger ribonucleic acidHourirritable bowel syndromeenteric nervous systemintracellular free calcium concentrationfluorescein isothiocyanateLaser Scanning Confocal MicroscopeCalcium
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Authors
A. Liñán-Rico, J.E. Wunderlich, J.T. Enneking, D.R. Tso, I. Grants, K.C. Williams, A. Otey, K. Michel, M. Schemann, B. Needleman, A. Harzman, F.L. Christofi,