| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5814743 | Neuropharmacology | 2013 | 7 Pages |
Abstract
⺠Nausea and vomiting are common side effects associated with GLP-1 receptor agonists. ⺠Administration of exendin-4 induces emesis and inhibits feeding in Suncus murinus. ⺠Exendin-4 may exert its effects via the hypothalamus and brainstem. ⺠Central GLP-1 receptors may represent an important physiological mediator of satiety and emesis.
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Authors
Sze Wa Chan, Ge Lin, David Tai Wai Yew, Chi Kong Yeung, John A. Rudd,