Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5814820 | Neuropharmacology | 2013 | 14 Pages |
Abstract
⺠Reviews the control of NMDAR functional properties by GluN2 subunits. ⺠Assesses structural elements of GluN2 subunits that determine NMDAR heterogeneity. ⺠Considers the utility of orthosteric and allosteric ligands acting at NMDARs. ⺠Potential of the NMDAR C-terminal domain as a novel therapeutic target is discussed.
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Authors
D.J.A. Wyllie, M.R. Livesey, G.E. Hardingham,