Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815032 | Neuropharmacology | 2013 | 9 Pages |
Abstract
⺠We examined SWDs in symptomatic WAG/Rij rats. ⺠Reduced expression of mGlu5 receptors in the ventrobasal thalamus. ⺠Increased expression of mGlu5 receptors in the somatosensory cortex. ⺠SWDs were not influenced by blockade of mGlu5 receptor. ⺠mGlu5 receptor potentiation with the novel enhancer, VU0360172 decreased SWDs.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
V. D'Amore, I. Santolini, C.M. van Rijn, F. Biagioni, G. Molinaro, A. Prete, P.J. Conn, C.W. Lindsley, Y. Zhou, P.N. Vinson, A.L. Rodriguez, C.K. Jones, S.R. Stauffer, F. Nicoletti, G. van Luijtelaar, R.T. Ngomba,