| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815039 | Neuropharmacology | 2013 | 7 Pages |
Abstract
⺠We examined postsynaptic mGluR actions in midbrain periaqueductal grey. ⺠Group I mGluR agonists activated most neurons, via mGluR1 and 5. ⺠Group II and II mGluR agonists inhibited a minority of neurons. ⺠Endogenously released glutamate also activated group I mGluR. ⺠These findings provide a basis for mGluR mediated analgesia in PAG.
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Authors
Adrianne R. Wilson-Poe, Vanessa A. Mitchell, Christopher W. Vaughan,