| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5815078 | Neuropharmacology | 2013 | 13 Pages |
Abstract
⺠Stimulation of 5-HTR7 in CNS neuronal primary cultures enhances neurite outgrowth. ⺠ERK and Cdk5 signaling pathways are required for 5-HTR7-dependent neurite outgrowth. ⺠5-HTR7-stimulated neurite outgrowth depends on de novo protein synthesis. ⺠MAP1B expression is strongly stimulated by activation of 5-HTR7.
Keywords
STRGad2HprtMAP1BNFLCHXCTXcdk5ERK5-HTNFM5-hydroxytryptamineattention deficit hyperactivity disorderStriatumgamma-aminobutyric acidADHDNeurite outgrowthembryonic agecycloheximidecyclin-dependent kinase 5Cortexneurofilament mediummapneurofilament lighthypoxanthine phosphoribosyltransferasemicrotubule-associated proteincytoskeletal proteinsExtracellular signal-regulated kinases 1/2GABA
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Authors
L. Speranza, A. Chambery, M. Di Domenico, M. Crispino, V. Severino, F. Volpicelli, M. Leopoldo, G.C. Bellenchi, U. di Porzio, C. Perrone-Capano,