Article ID Journal Published Year Pages File Type
5815104 Neuropharmacology 2013 7 Pages PDF
Abstract
► Activation of neuronal P2X3 receptor is essential to the hyperalgesia. ► The P2X3 receptor activation leads to PKCɛ translocation. ► P2X3 primes the primary afferent neuron, increasing its response. ► Endogenous prostaglandin does not promote hyperalgesia by itself.
Keywords
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Preview
Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation
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