Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815131 | Neuropharmacology | 2013 | 12 Pages |
Abstract
⺠GABA release is larger in msP rats compared to Sprague Dawley and Wistar rats. ⺠Ethanol- and CRF-induced increase in CeA GABA release is comparable in the 3 rat lines. ⺠CRF1 antagonist-induced decrease in GABA release is comparable in the 3 rat lines. ⺠msP rats with history of ethanol show enhanced GABA release compared to naïve msP. ⺠History of ethanol abolishes the CRF1 antagonist-induced decrease in GABA release.
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Authors
Melissa A. Herman, Marsida Kallupi, George Luu, Christopher S. Oleata, Markus Heilig, George F. Koob, Roberto Ciccocioppo, Marisa Roberto,