Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5815234 | Neuropharmacology | 2013 | 9 Pages |
Abstract
⺠Alpha7 positive allosteric modulators are anti-inflammatory. ⺠PNU-120596 reversed carrageenan-induced thermal hyperalgesia and paw edema. ⺠PNU-120595 anti-inflammatory effects were α7 receptor-mediated. ⺠NS1738 did not attenuate hyperalgesia and allodynia in the CCI model. âºÂ PNU-120596 reversed thermal hyperalgesia and allodynia in the CCI model.
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Authors
Kelen Freitas, Sudeshna Ghosh, F. Ivy Carroll, Aron H. Lichtman, M. Imad Damaj,